Regenerative aesthetics is changing the beauty world and Biostimulators are leading the movement. Unlike traditional fillers that simply add volume, biostimulators work with your body to rebuild what time has softened. They gradually restore firmness, elasticity, and youthful structure by stimulating your own collagen production. The result? A refreshed, natural look that isn’t “obvious” or overdone. Patients who want natural-looking rejuvenation without looking "treated" gravitate towards Biostimulators for good reason.
At Martin’s Rejuvenation Centre, we specialize in treatments that support authentic, confident beauty. With advanced medical aesthetic techniques, modern technologies, and a personalized approach, we help you look renewed, refreshed and rejuvenated. .
If you’re curious whether Biostimulators are right for you, you can book a consultation to explore your personalized options.
Biostimulators, such as Sculptra and Radiesse, are injectable treatments that stimulate your skin to rebuild its own collagen and elastin. These two proteins keep skin firm, lifted, and youthful. Unlike fillers that add immediate volume, biostimulators strengthen the deeper layers of the skin, giving you gradual, natural-looking rejuvenation that lasts. They’re perfect for anyone who wants to look fresher and more lifted without looking like they’ve had treatment done.
Biostimulators activate fibroblasts, the cells that create collagen. Once injected, tiny particles signal your skin to start repairing and rebuilding its internal structure. Over the next few months, the skin becomes firmer, smoother, tighter, and more resilient, with results that continue to improve over time.
Biostimulator injections typically contain either poly-L-lactic acid (PLLA) used in Sculptra or calcium hydroxylapatite (CaHA) used in Radiesse. Both ingredients are safe, biocompatible, and have been used in medicine for decades. As your body absorbs them, they leave behind fresh, new collagen that strengthens and rejuvenates your skin naturally.
Collagen production decreases by about one percent per year starting in our mid-20s. Sun exposure, stress, and environmental factors accelerate this decline. This leads to: collagen weakens, patients notice sagging skin, wrinkles, thinning skin, and changes in texture. Biostimulators help reverse this decline by restoring your skin’s ability to rebuild itself.
Fillers and biostimulators both rejuvenate the face, but in totally different ways:
Most patients benefit from a combination of both, depending on their goals.
Fillers are best for restoring lost volume in targeted areas like cheeks and lips, while biostimulators work across larger regions of the face and body to improve overall firmness, elasticity, and texture.
Fillers create contour and lift immediately. They sharpen jawlines, build cheekbones, and smooth deeper folds. Biostimulators, by contrast, strengthen the internal scaffolding of the skin. Think of them as a long-term investment in healthier, stronger tissue.
Choosing between fillers and biostimulators can be difficult to determine on your own. . During your consultation, we will examine your specific facial anatomy, skin thickness, elasticity, and areas of concern before recommending a personalized plan. We will always discuss the best treatment plan for you, with you, to ensure we are on the same page about your results before we begin your treatment. And we always aim for natural, balanced and beautiful outcomes.
The two most common biostimulators we use in medical aesthetics today are PLLA-based and CaHA-based formulas.
PLLA is known for delivering gradual, long-term results. These biostimulants are designed to restore the lost collagen that contributes to volume decline and laxity. They are ideal for the cheeks, temples, lower face, and even large body areas like buttocks or thighs.
CaHA is a versatile option that boosts both collagen and elastin. Products containing CaHA improve texture, firmness, and overall skin tone. When diluted, CaHA becomes extremely effective for treating the thin, crepey skin on the neck, chest, arms, and abdomen.
Our injectors select the right treatments for you based on skin quality, current aging changes, treatment area, and long-term goals. Ensuring a personalized approach helps maintain natural-looking results and supports healthy collagen formation.
Biostimulators will tackle skin rejuvenation differently than traditional fillers. Instead of filling in lines, biostimulators will improve the biological processes that keep skin healthy.
As collagen rebuilds, the skin becomes naturally lifted and tighter—without looking overfilled.
Thinning, rough, or dull skin becomes thicker, smoother, and more vibrant. Biostimulators can also help soften acne scars.
Biostimulators return youthful structure without adding heaviness, giving a subtle, refreshed outcome.
Because they work on skin quality rather than simply adding volume , biostimulators can be used on the face, neck, chest, hand and multiple body areas to restore firmness and elasticity.
As collagen decreases with our natural aging process, patients notice sagging, wrinkles, and hollowing. Biostimulators for skin help rebuild the internal support matrix , making the face look smoother, firmed and naturally refreshed. We often pair these treatments with wrinkle relaxers, such as Botox, Nuceiva, Dysport and Xeomin for even better results.
These delicate areas respond extremely well to CaHA-based Biostimulators. Patients see smoother texture, improved firmness, and a beautifully blended, youthful appearance.
Crepey or thinning skin on the body can be difficult to treat. Biostimulators help strengthen tissue and restore elasticity. When paired with technology like Secret-RF and Fotona lasers treatments, results can be even more transformative.
We prioritize clarity and comfort throughout the entire treatment process so you always feel informed and confident in the process..
We evaluate your skin’s thickness, elasticity, texture, and areas of concern. During the consultation, we may also discuss complementary options like neuromodulators or energy devices to enhance your results .
We choose a needle or cannula depending on the area being treated. Most patients find the process quick and well-tolerated. Our expert injectors and advanced injection techniques ensure even, natural-looking collagen stimulation
You may experience mild swelling or tenderness for a short period. Some Biostimulators include a simple massage routine afterward to optimize results. Collagen production begins soon after treatment and continues to improve gradually over the following months.
YES! Biostimulators have long-standing safety records in both aesthetic and medical use for decades.
PLLA and CaHA have extensive clinical safety data. They are biocompatible, gradually absorbed by the body, and used worldwide in regenerative aesthetic medicine.
Common side effects include temporary swelling or bruising. Rarely small nodules can appear if aftercare is not followed. Our expert injectors, trained in advanced injection techniques, use advanced techniques and thorough aftercare guidance to ensure the safest possible experience and best results possible.
Biostimulators are ideal for people experiencing; mild to moderate laxity, early volume softening, thinning or crepey skin, fine lines or textural changes or early signs of aging. They’re also popular among younger patients who want to prevent visible aging by maintaining collagen levels.
One of the biggest advantages of biostimulators is longevity.Collagen Production & Treatment Timeline
Most patients typically begin to see improvements six to eight weeks after treatment, with full results appearing between three to six months.
PLLA results may last up to two years. CaHA usually lasts twelve to eighteen months. Because your own body is doing the work, results can last even longer depending on your lifestyle and skincare habits.
We typically recommend maintenance every one to two years depending on age, goals, and collagen quality. Supporting your skin with high-quality medical-grade skincare products can help prolong results.
Biostimulators are a powerful and natural approach to skin rejuvenation.If you want smoother, firmer, healthier-looking skin—without looking “done”—this treatment may be the perfect fit. Treatments like resurfacing lasers, neuromodulators, and energy-based skin tightening blend well with biostimulators. Feel free to reach out through our contact us page to explore combined treatment plans.
Our team at Martin’s Rejuvenation Centre focuses on subtle, effective, long-lasting results. Your refreshed skin is one step away. Book a consultation to get started.